By Professor Dietmar Schomburg, Dr. Ida Schomburg, Dr. Antje Chang (eds.)

Springer instruction manual of Enzymes offers information on enzymes sufficiently good characterised. It deals concise and entire descriptions of a few 5,000 enzymes and their software components. information sheets are prepared of their EC-Number series and the volumes themselves are prepared in line with enzyme classes.

This new, moment version displays massive growth in enzymology: many enzymes are newly categorized or reclassified. every one access is correlated with references and a number of resource organisms. New datafields are created: software and engineering (for the homes of enzymes the place the series has been changed). the complete quantity of fabric inside the instruction manual has greater than doubled in order that the entire moment variation comprises 39 volumes in addition to a Synonym Index. additionally, beginning in 2009, all newly labeled enzymes are handled in complement Volumes.

Springer instruction manual of Enzymes is a perfect resource of data for researchers in biochemistry, biotechnology, natural and analytical chemistry, and nutrition sciences, in addition to for medicinal applications.

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Additional resources for Class 2 Transferases: EC 2.7.11.1–2.7.11.16

Example text

G. 1 Non-specific serine/threonine protein kinase P ADP + phosphorylated RSRSRSRSRSRSPPPVSK S ATP + S6 protein of the 40s ribosomal subunit <53> (<53> the mitogenactivated protein kinase plays a central role in the control of mRNA translation. ) [471] P ADP + phosphorylated SIV/17E-Fr Nef protein S ATP + SR protein <225, 226, 227, 228, 229, 230, 231> (<225> dsk1 protein may play an important role in mitotic control by altering cellular location, degree of phosphorylation and kinase activity [311]; <231> enzyme acts as a corepressors for homeodomain transcription factors [320]; <231> enzyme regulates the activation and adhesion of T cells.

E. ) [148] ADP + ? ) [285] ADP + ? ) [245] ADP + ? ) [177] ADP + ? ) [372] P ADP + ? ) [372] P ADP + ? e. g. 1 Non-specific serine/threonine protein kinase P ADP + phosphorylated RSRSRSRSRSRSPPPVSK S ATP + S6 protein of the 40s ribosomal subunit <53> (<53> the mitogenactivated protein kinase plays a central role in the control of mRNA translation. ) [471] P ADP + phosphorylated SIV/17E-Fr Nef protein S ATP + SR protein <225, 226, 227, 228, 229, 230, 231> (<225> dsk1 protein may play an important role in mitotic control by altering cellular location, degree of phosphorylation and kinase activity [311]; <231> enzyme acts as a corepressors for homeodomain transcription factors [320]; <231> enzyme regulates the activation and adhesion of T cells.

Bub1 also has a crucial role in normal, unperturbed mitoses. Loss of bub1 function causes chromosomes to lag on the anaphase spindle and an increased frequency of chromosome loss. 1 for degradation by proteosomes during mitosis [360]; <251> the enzyme is involved in spindle assembly during the cell cycle [363]; <249> hBUBR1 may regulate multiple functions that include the kinetochore and the spindle midzone [361]; <247> kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage [354]; <248> hBub1 is an important component of the spindle checkpoint pathway.

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