By Srijoy Mahapatra (auth.), Igor R. Efimov PhD, Mark W. Kroll PhD, Patrick J. Tchou MD (eds.)
Pacing and defibrillation became the major healing remedies of middle rhythm issues, together with bradycardia and tachycardia. The heritage of the winning improvement of bioelectric treatments comprises the improvement of experimental and theoretical methodologies, novel bioengineering techniques and cutting-edge medical implantable gadget remedies. This quantity will current a uniform thematic choice of stories written through the major easy and utilized scientists operating in easy bioengineering examine laboratories, who've contributed to the improvement of present realizing of the basic mechanisms of pacing and electrophysiology, and who're on the innovative of extra advancements in electrotherapy.
Igor R. Efimov, Ph.D., is affiliate Professor of Biomedical Engineering, Washington college, St. Louis, Missouri.
Mark W. Kroll, Ph.D., is Adjunct Professor Biomedical Engineering, California Polytechnic collage and collage of Minnesota..
Patrick J. Tchou, M.D. is within the part of Cardiac Electrophysiology and Pacing on the Cleveland health center in Cleveland, Ohio.
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Extra resources for Cardiac Bioelectric Therapy: Mechanisms and Practical Implications
Ever on the borderline between desire and discomfort, electric resuscitation continuously struggled for legitimacy in the public comprehension, against allegations of sorcery on one side and quackery on the other. 12 Still, the ﬁeld suﬀered from a grave setback: the History of Deﬁbrillation Figure 3: Portable galvanic resuscitation mechanism, nineteenth century 21 22 Hana Akselrod et al. general lack of explanation for what the current was doing to the heart and how. Further advances would have to wait until the elucidation of the physiological mechanism.
Therapeutic uses of atrial pacing. Am Heart J 1973;73:835–840 22. Castillo C. Bifocal demand pacing. Chest 1971;59:360–364 23. Belott PH. A variation on the introducer technique for unlimited access to the subclavian vein. PACE 1981;4:43–48 24. Kastor JA. Michel Mirowski and the automatic implantable deﬁbrillator. Am J Cardiol 1989;63:977–982 and 1121–1126 25. Jeﬀerey K. Machines in Our Hearts. 2 History of Deﬁbrillation Hana Akselrod, Mark W. Kroll, and Michael V. 1 One of the ﬁrst descriptions of ventricular ﬁbrillation and its link to sudden cardiac death belongs to the British physiologist John A.
In 1947 Beck successfully performed the ﬁrst documented deﬁbrillation on a human patient. Richard Heyard, aged 14, was undergoing surgery to correct a “hollow chest” breastbone malformation. Near the end of the procedure, his heart suddenly entered ventricular ﬁbrillation. The surgeon immediately started direct heart massage, keeping Heyard’s blood in circulation, but the ﬁbrillation showed no indication of stopping spontaneously. Beck requested permission to perform his experimental procedure, connecting two electrodes directly to Heyard’s exposed heart.