By Dr. H. Krebs, Prof. Dr. W. Schramm (auth.), Professor Dr. med. I. Scharrer, Professor Dr. med. W. Schramm (eds.)

This e-book includes the contributions to the thirty fourth Hemophilia Symposium, Hamburg 2003. the most themes are HIV an infection and epidemiology, administration of bleedings in hemophiliacs with inhibitors, orthopedic difficulties and remedy in hemophiliacs, remedy with protein C and pediatric hemostaseology. the amount is rounded off by means of a variety of loose papers and posters on hemophilia, hemophiliacs with inhibitors, thrombophilia and molecular diagnostics.

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In the past, several central venous lines (two Broviak-catheters and 4 port-a-cath systems) had been implanted. The actual port-a-cath was occluded by a thrombus and treatment of bleedings became impossible because of lack of venous access. Once more, a port-a-cath implantation was indicated. Table 3. Clinical status of the patient’s joints using the Neutral-0-Method Hemophilic arthropathy Right knee E/F 0 - 5 - 140° Left knee E/F 0 - 10 - 140° Right ankle E/F 0 - 5 - 40°, reduced movement Left ankle E/F 0 - 5 - 30°, reduced movement Right elbow E/F 0 – 20 - 130° Left elbow E/F 0 – 0 - 135° Pronation/Supination normal (E=extension, F=flexion).

Acute renal failure due to high-grade obstruction following therapy with epsilon-aminocaproic acid. Am J Kidney Dis. 1986;8(6):441-4. 54. Schultz M, van der Lelie H. Microscopic haematuria as a relative contraindication for tranexamic acid. Br J Haematol. 1995;89(3):663-4. 55. Cattaneo M, Mannucci PM. Current status of non-transfusional haemostatic agents. Haematological 1999. 84 (Suppl EHA-4):120-123. 56. Schulman S, d’Oiron R, Martinowitz U, Pasi J, Briquel ME, Mauser-Bunschoten E, Morfini M, Ritchie B, Goudemand J, Lloyd J, McPherson J, Negrier C, Peerlinck K, Petrini P, Tusell J.

Blood. 2002 Sep 1;100(5):1584-9. 5. Lee C, Dusheiko G: The natural history and antiviral treatment of hepatitis C in haemophilia. Haemophilia. 2002 May;8(3):322-9. 6. Quintana M, del Amo J, Barrasa A, Perez-Hoyos S, Ferreros I, Hernandez F, Villar A, Jimenez V, Bolumar F: Progression of HIV infection and mortality by hepatitis C infection in patients with haemophilia over 20 years. Haemophilia. 2003 Sep;9(5):605-12. 7. Ragni MV, Belle SH: Impact of human immunodeficiency virus infection on progression to end-stage liver disease in individuals with hemophilia and hepatitis C virus infection.

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